Publikationen von Sarah O’Connor

Walter, A.; Caputi, L.; O’Connor, S.; van Pée, K.-H.; Ludwig-Müller, J.: Chlorinated auxins–how does Arabidopsis thaliana deal with them? International Journal of Molecular Sciences 21 (7), 2567 (2020)

Farrow, S. C.; Kamileen, M. O.; Caputi, L.; Bussey, K.; Mundy, J. E. A.; McAtee, R. C.; Stephenson, C. R. J.; O’Connor, S. E.: Biosynthesis of an anti-addiction agent from the iboga plant. Journal of the American Chemical Society 141 (33), S. 12979 - 12983 (2019)

Franke, J.; Kim, J.; Hamilton, J. P.; Zhao, D.; Pham, G. M.; Wiegert-Rininger, K.; Crisovan, E.; Newton, L.; Vaillancourt, B.; Tatsis, E. et al.; Buell, C. R.; O'Connor, S. E.: Gene discovery in Gelsemium highlights conserved gene clusters in monoterpene indole alkaloid biosynthesis. Chembiochem 20 (1), S. 83 - 87 (2019)

Johnson, S. R.; Bhat, W. W.; Bibik, J.; Turmo, A.; Hamberger, B.; Mint Evolutionary Genomics Consortium; Hamberger, B.: A database-driven approach identifies additional diterpene synthase activities in the mint family (Lamiaceae). The Journal of Biological Chemistry 294 (4), S. 1349 - 1362 (2019)

Lichman, B. R.; Kamileen, M. O.; Titchiner, G. R.; Saalbach, G.; Stevenson, C. E. M.; Lawson, D. M.; O'Connor, S. E.: Uncoupled activation and cyclization in catmint reductive terpenoid biosynthesis. Nature Chemical Biology 15, S. 71 - 79 (2019)

Lichman, B. R.; O’Connor, S. E.; Kries, H.: Biocatalytic strategies towards [4+2] cycloadditions. Chemistry – A European Journal 25 (28), S. 6864 - 6877 (2019)

Yamamoto, K.; Takahashi, K.; Caputi, L.; Mizuno, H.; Rodriguez-Lopez, C. E.; Iwasaki, T.; Ishizaki, K.; Fukaki, H.; Ohnishi, M.; Yamazaki, M. et al.; Masujima, T.; O’Connor, S. E.; Mimura, T.: The complexity of intercellular localisation of alkaloids revealed by single-cell metabolomics. New Phytologist 224 (2), S. 848 - 859 (2019)

Mint Evolutionary Genomics Consortium: Phylogenomic mining of the mints: elucidating evolution in a chemically diverse clade. Molecular Plant 11 (8), S. 1084 - 1096 (2018)

Caputi, L.; Franke, J.; Farrow, S. C.; Chung, K.; Payne, R. M. E.; Nguyen, T.-D.; Dang, T.-T. T.; Carqueijeiro, I. S. T.; Koudounas, K.; de Bernonville, T. D. et al.; Ameyaw, B.; Jones, D. M.; Vieira, I. J. C.; Courdavault, V.; O'Connor, S. E.: Missing enzymes in the biosynthesis of the anticancer drug vinblastine in Madagascar periwinkle. Science 360 (6394), S. 1235 - 1238 (2018)

Carqueijeiro, I.; Brown, S.; Chung, K.; Dang, T.-T.; Walia, M.; Besseau, S.; de Bernonville, T. D.; Oudin, A.; Lanoue, A.; Billet, K. et al.; Munsch, T.; Koudounas, K.; Melin, C.; Godon, C.; Razafimandimby, B.; de Craene, J.-O.; Glévarec, G.; Marc, J.; Giglioli-Guivarc’h, N.; Clastre, M.; St-Pierre, B.; Papon, N.; Andrade, R. B.; O'Connor, S. E.; Courdavaulta, V.: Two tabersonine 6,7-epoxidases start synthesis of lochnericine-type alkaloids in Catharanthus roseus. Plant Physiology 177 (4), S. 1473 - 1486 (2018)

Carqueijeiro, I.; de Bernonville, T. D.; Lanoue, A.; Dang, T.-T.; Teijaro, C.; Paetz, C.; Billet, K.; Mosquera, A.; Oudin, A.; Besseau, S. et al.; Papon, N.; Glévarec, G.; Atehortùa, L.; Clastre, M.; Giglioli-Guivarc'h, N.; Schneider, B.; St-Pierre, B.; Andrade, R. B.; O’Connor, S. E.; Courdavault, V.: A BAHD acyltransferase catalyzing 19-O-acetylation of tabersonine derivatives in roots of Catharanthus roseus enables combinatorial synthesis of monoterpene indole alkaloids. The Plant Journal 49 (3), S. 469 - 484 (2018)

Casini, A.; Chang, F.-Y.; Eluere, R.; King, A. M.; Young, E. M.; Dudley, Q. M.; Karim, A.; Pratt, K.; Bristol, C.; Forget, A. et al.; Ghodasara, A.; Warden-Rothman, R.; Gan, R.; Cristofaro, A.; Borujeni, A. E.; Ryu, M.-H.; Li, J.; Kwon, Y.-C.; Wang, H.; Tatsis, E.; Rodriguez-Lopez, C.; O'Connor, S. E.; Medema, M. H.; Fischbach, M. A.; Jewett, M. C.; Voigt, C.; Gordon, D. B.: A pressure test to make 10 molecules in 90 days: external evaluation of methods to engineer biology. Journal of the American Chemical Society 140 (12), S. 4302 - 4316 (2018)

Dang, T.-T. T.; Franke, J.; Carqueijeiro, I. S. T.; Langley, C.; Courdavault, V.; O'Connor, S. E.: Sarpagan bridge enzyme has substrate-controlled cyclization and aromatization modes. Nature Chemical Biology 14 (8), S. 760 - 763 (2018)

Farrow, S. C.; Kamileen, M. O.; Meades, J.; Ameyaw, B.; Xiao, Y.; O'Connor, S. E.: Cytochrome P450 and O-methyltransferase catalyze the final steps in the biosynthesis of the anti-addictive alkaloid ibogaine from Tabernanthe iboga. The Journal of Biological Chemistry 293 (36), S. 13821 - 13833 (2018)

Sherden, N. H.; Lichman, B.; Caputi, L.; Zhao, D.; Kamileen, M. O.; Buell, C. R.; O'Connor, S. E.: Identification of iridoid synthases from Nepeta species: Iridoid cyclization does not determine nepetalactone stereochemistry. Phytochemistry 145, S. 48 - 56 (2018)

Stavrinides , A. K.; Tatsis , E. C.; Dang, T.-T.; Caputi, L.; Stevenson, C. E. M.; Lawson, D. M.; Schneider, B.; O'Connor, S. E.: Discovery of a short-chain dehydrogenase from Catharanthus roseus that produces a new monoterpene indole alkaloid. Chembiochem 19 (9), S. 940 - 948 (2018)

Dang, T.-T. T.; Franke, J.; Tatsis, E.; O'Connor, S. E.: Dual catalytic activity of a cytochrome P450 controls bifurcation at a metabolic branch point of alkaloid biosynthesis in Rauwolfia serpentina. Angewandte Chemie International Edition 56 (32), S. 9440 - 9444 (2017)

de Bernonville, T. D.; Carqueijeiro, I.; Lanoue, A.; Lafontaine, F.; Bel, P. S.; Liesecke, F.; Musset, K.; Oudin, A.; Glevarec, G.; Pichon, O. et al.; Besseau, S.; Clastre, M.; St-Pierre, B.; Flors, V.; Maury, S.; Huguet, E.; O'Connor, S. E.; Courdavault, V.: Folivory elicits a strong defense reaction in Catharanthus roseus: metabolomic and transcriptomic analyses reveal distinct local and systemic responses. Scientific Reports 7, 40453 (2017)

Kries, H.; Kellner, F.; Kamileen, M. O.; O'Connor, S. E.: Inverted stereocontrol of iridoid synthase in snapdragon. The Journal of Biological Chemistry 292 (35), S. 14659 - 14667 (2017)

Larsen, B.; Fuller, V. L.; Pollier, J.; Moerkercke, A. V.; Schweizer, F.; Payne, R.; Colinas, M.; O'Connor, S. E.; Goossens, A.; Halkier, B. A.: Identification of iridoid glucoside transporters in Catharanthus roseus. Plant and Cell Physiology 58 (9), S. 1507 - 1518 (2017)