Publications of Sarah E. O’Connor

de Bernonville, T. D.; Maury, S.; Delaunay, A.; Daviaud, C.; Chaparro, C.; Tost, J.; O’Connor, S. E.; Courdavault, V.: Developmental methylome of the medicinal plant Catharanthus roseus unravels the tissue-specific control of the monoterpene indole alkaloid pathway by DNA methylation. International Journal of Molecular Sciences 21 (17), 6028 (2020)

de Bernonville, T. D.; Papon, N.; Clastre, M.; O’Connor, S. E.; Courdavault, V.: Identifying missing biosynthesis enzymes of plant natural products. Trends in Pharmacological Sciences 41 (3), pp. 142 - 146 (2020)

Lichman, B. R.; Godden, G. T.; Hamilton, J. P.; Palmer, L.; Kamileen, M. O.; Zhao, D.; Vaillancourt, B.; Wood, J. C.; Sun, M.; Kinser, T. J. et al.; Henry, L. K.; Rodriguez Lopez, C. E.; Dudareva, N.; Soltis, D. E.; Soltis, P. S.; Buell, C. R.; O’Connor, S. E.: The evolutionary origins of the cat attractant nepetalactone in catnip. Science Advances 6 (20), eaba0721 (2020)

Neumann, M.; Prahl, S.; Caputi, L.; Hill, L.; Kular, B.; Walter, A.; Patallo, E. P.; Milbredt, D.; Aires, A.; Schöpe, M. et al.; O’Connor, S. E.; van Pée, K.-H.; Ludwig-Müller, J.: Hairy root transformation of Brassica rapa with bacterial halogenase genes and regeneration to adult plants to modify production of indolic compounds. Phytochemistry 175, 112371 (2020)

Nguyen, T.-D.; O’Connor, S. E.: The progesterone 5 beta-reductase/iridoid synthase family: A catalytic reservoir for specialized metabolism across land plants. ACS Chemical Biology 15 (7), pp. 1780 - 1787 (2020)

Stander, E. A.; Sepúlveda, L. J.; de Bernonville, T. D.; Carqueijeiro, I.; Koudounas, K.; Cruz, P. L.; Besseau, S.; Lanoue, A.; Papon, N.; Giglioli-Guivarc’h, N. et al.; Dirks, R.; O’Connor, S. E.; Atehortùa, L.; Oudin, A.; Courdavault, V.: Identifying genes involved in alkaloid biosynthesis in Vinca minor through transcriptomics and gene co-expression analysis. Biomolecules 10 (12), 1595 (2020)

Walia, M.; Teijaro, C. N.; Gardner, A.; Tran, T.; Kang, J.; Zhao, S.; O’Connor, S. E.; Courdavault, V.; Andrade, R. B.: Synthesis of (−)-melodinine K: A case study of efficiency in natural product synthesis. Journal of Natural Products 83 (8), pp. 2425 - 2433 (2020)

Walter, A.; Caputi, L.; O’Connor, S.; van Pée, K.-H.; Ludwig-Müller, J.: Chlorinated auxins–how does Arabidopsis thaliana deal with them? International Journal of Molecular Sciences 21 (7), 2567 (2020)

Farrow, S. C.; Kamileen, M. O.; Caputi, L.; Bussey, K.; Mundy, J. E. A.; McAtee, R. C.; Stephenson, C. R. J.; O’Connor, S. E.: Biosynthesis of an anti-addiction agent from the iboga plant. Journal of the American Chemical Society 141 (33), pp. 12979 - 12983 (2019)

Franke, J.; Kim, J.; Hamilton, J. P.; Zhao, D.; Pham, G. M.; Wiegert-Rininger, K.; Crisovan, E.; Newton, L.; Vaillancourt, B.; Tatsis, E. et al.; Buell, C. R.; O'Connor, S. E.: Gene discovery in Gelsemium highlights conserved gene clusters in monoterpene indole alkaloid biosynthesis. Chembiochem 20 (1), pp. 83 - 87 (2019)

Johnson, S. R.; Bhat, W. W.; Bibik, J.; Turmo, A.; Hamberger, B.; Mint Evolutionary Genomics Consortium; Hamberger, B.: A database-driven approach identifies additional diterpene synthase activities in the mint family (Lamiaceae). The Journal of Biological Chemistry 294 (4), pp. 1349 - 1362 (2019)

Lichman, B. R.; Kamileen, M. O.; Titchiner, G. R.; Saalbach, G.; Stevenson, C. E. M.; Lawson, D. M.; O'Connor, S. E.: Uncoupled activation and cyclization in catmint reductive terpenoid biosynthesis. Nature Chemical Biology 15, pp. 71 - 79 (2019)

Lichman, B. R.; O’Connor, S. E.; Kries, H.: Biocatalytic strategies towards [4+2] cycloadditions. Chemistry – A European Journal 25 (28), pp. 6864 - 6877 (2019)

Yamamoto, K.; Takahashi, K.; Caputi, L.; Mizuno, H.; Rodriguez-Lopez, C. E.; Iwasaki, T.; Ishizaki, K.; Fukaki, H.; Ohnishi, M.; Yamazaki, M. et al.; Masujima, T.; O’Connor, S. E.; Mimura, T.: The complexity of intercellular localisation of alkaloids revealed by single-cell metabolomics. New Phytologist 224 (2), pp. 848 - 859 (2019)

Mint Evolutionary Genomics Consortium: Phylogenomic mining of the mints: elucidating evolution in a chemically diverse clade. Molecular Plant 11 (8), pp. 1084 - 1096 (2018)

Caputi, L.; Franke, J.; Farrow, S. C.; Chung, K.; Payne, R. M. E.; Nguyen, T.-D.; Dang, T.-T. T.; Carqueijeiro, I. S. T.; Koudounas, K.; de Bernonville, T. D. et al.; Ameyaw, B.; Jones, D. M.; Vieira, I. J. C.; Courdavault, V.; O'Connor, S. E.: Missing enzymes in the biosynthesis of the anticancer drug vinblastine in Madagascar periwinkle. Science 360 (6394), pp. 1235 - 1238 (2018)

Carqueijeiro, I.; Brown, S.; Chung, K.; Dang, T.-T.; Walia, M.; Besseau, S.; de Bernonville, T. D.; Oudin, A.; Lanoue, A.; Billet, K. et al.; Munsch, T.; Koudounas, K.; Melin, C.; Godon, C.; Razafimandimby, B.; de Craene, J.-O.; Glévarec, G.; Marc, J.; Giglioli-Guivarc’h, N.; Clastre, M.; St-Pierre, B.; Papon, N.; Andrade, R. B.; O'Connor, S. E.; Courdavaulta, V.: Two tabersonine 6,7-epoxidases start synthesis of lochnericine-type alkaloids in Catharanthus roseus. Plant Physiology 177 (4), pp. 1473 - 1486 (2018)

Carqueijeiro, I.; de Bernonville, T. D.; Lanoue, A.; Dang, T.-T.; Teijaro, C.; Paetz, C.; Billet, K.; Mosquera, A.; Oudin, A.; Besseau, S. et al.; Papon, N.; Glévarec, G.; Atehortùa, L.; Clastre, M.; Giglioli-Guivarc'h, N.; Schneider, B.; St-Pierre, B.; Andrade, R. B.; O’Connor, S. E.; Courdavault, V.: A BAHD acyltransferase catalyzing 19-O-acetylation of tabersonine derivatives in roots of Catharanthus roseus enables combinatorial synthesis of monoterpene indole alkaloids. The Plant Journal 49 (3), pp. 469 - 484 (2018)

Casini, A.; Chang, F.-Y.; Eluere, R.; King, A. M.; Young, E. M.; Dudley, Q. M.; Karim, A.; Pratt, K.; Bristol, C.; Forget, A. et al.; Ghodasara, A.; Warden-Rothman, R.; Gan, R.; Cristofaro, A.; Borujeni, A. E.; Ryu, M.-H.; Li, J.; Kwon, Y.-C.; Wang, H.; Tatsis, E.; Rodriguez-Lopez, C.; O'Connor, S. E.; Medema, M. H.; Fischbach, M. A.; Jewett, M. C.; Voigt, C.; Gordon, D. B.: A pressure test to make 10 molecules in 90 days: external evaluation of methods to engineer biology. Journal of the American Chemical Society 140 (12), pp. 4302 - 4316 (2018)

Dang, T.-T. T.; Franke, J.; Carqueijeiro, I. S. T.; Langley, C.; Courdavault, V.; O'Connor, S. E.: Sarpagan bridge enzyme has substrate-controlled cyclization and aromatization modes. Nature Chemical Biology 14 (8), pp. 760 - 763 (2018)