Publications of Sarah E. O'Connor

de Bernonville, T. D.; Carqueijeiro, I.; Lanoue, A.; Lafontaine, F.; Bel, P. S.; Liesecke, F.; Musset, K.; Oudin, A.; Glevarec, G.; Pichon, O. et al.; Besseau, S.; Clastre, M.; St-Pierre, B.; Flors, V.; Maury, S.; Huguet, E.; O'Connor, S. E.; Courdavault, V.: Folivory elicits a strong defense reaction in Catharanthus roseus: metabolomic and transcriptomic analyses reveal distinct local and systemic responses. Scientific Reports 7, 40453 (2017)

Kries, H.; Kellner, F.; Kamileen, M. O.; O'Connor, S. E.: Inverted stereocontrol of iridoid synthase in snapdragon. Journal of Biological Chemistry 292 (35), pp. 14659 - 14667 (2017)

Larsen, B.; Fuller, V. L.; Pollier, J.; Moerkercke, A. V.; Schweizer, F.; Payne, R.; Colinas, M.; O'Connor, S. E.; Goossens, A.; Halkier, B. A.: Identification of iridoid glucoside transporters in Catharanthus roseus. Plant and Cell Physiology 58 (9), pp. 1507 - 1518 (2017)

Leisner, C. P.; Kamileen, M. O.; Conway, M. E.; O'Connor, S. E.; Buell, C. R.: Differential iridoid production as revealed by a diversity panel of 84 cultivated and wild blueberry species. PLoS One 12 (6), e0179417 (2017)

Patallo, E. P.; Walter, A.; Milbredt, D.; Thomas, M.; Neumann, M.; Caputi, L.; O'Connor, S. E.; Ludwog-Müller, J.; van Pée, K.-H.: Strategies to produce chlorinated indole-3-acetic acid and indole-3-acetic acid intermediates. ChemistrySelect 2 (34), pp. 11148 - 11153 (2017)

Payne, R. M. E.; Xu, D.; Foureau, E.; Carqueijeiro, M. I. S. T.; Oudin, A.; de Bernonville, T. D.; Novak, V.; Burow, M.; Olsen, C.-E.; Jones, D. M. et al.; Tatsis, E. C.; Pendle, A.; Halkier, B. A.; Geu-Flores, F.; Courdavault, V.; Nour-Eldin, H. H.; O’Connor, S. E.: An NPF transporter exports a central monoterpene indole alkaloid intermediate from the vacuole. Nature 3, 16208 (2017)

Alagna, F.; Geu-Flores, F.; Kries, H.; Panara, F.; Baldoni, L.; O'Connor, S. E.; Osbourn, A.: Identification and characterization of the iridoid synthase involved in oleuropein biosynthesis in olive (Olea europaea) fruits. The Journal of Biological Chemistry 291 (11), pp. 5542 - 5554 (2016)

Jakubczyk, D.; Caputi, L.; Stevenson, C. E. M.; Lawson, D. M.; O'Connor, S. E.: Structural characterization of EasH (Aspergillus japonicus) - an oxidase involved in cycloclavine biosynthesis. Chemical Communications 52 (99), pp. 14306 - 14309 (2016)

Kries, H.; Caputi, L.; Stevenson, C. E. M.; Kamileen, M. O.; Sherden, N. H.; Geu-Flores, F.; Lawson, D. M.; O'Connor, S. E.: Structural determinants of reductive terpene cyclization in iridoid biosynthesis. Nature Chemical Biology 12 (1), pp. 6 - 8 (2016)

Kries, H.; O'Connor, S. E.: Biocatalysts from alkaloid producing plants. Current Opinion in Chemical Biology 31, pp. 22 - 30 (2016)

Parage, C.; Foureau, E.; Kellner, F.; Burlat, V.; Mahroug, S.; Lanoue, A.; Duge de Bernonville, T.; Arias Londono, M.; Carqueijeiro, I.; Oudin, A. et al.; Besseau, S.; Papon, N.; Glevarec, G.; Atehortua, L.; Giglioli-Guivarc'h, N.; St-Pierre, B.; Clastre, M.; O'Connor, S. E.; Courdavault, V.: Class II cytochrome P450 reductase governs the biosynthesis of alkaloids. Plant Physiology 172 (3), pp. 1563 - 1577 (2016)

Stavrinides, A.; Tatsis, E. C.; Caputi, L.; Foureau, E.; Stevenson, C. E. M.; Lawson, D. M.; Courdavault, V.; O'Connor, S. E.: Structural investigation of heteroyohimbine alkaloid synthesis reveals active site elements that control stereoselectivity. Nature Communications 7, 12116 (2016)

Tatsis, E. C.; O'Connor, S. E.: New developments in engineering plant metabolic pathways. Current Opinion in Biotechnology 42, pp. 126 - 132 (2016)

Brown, S.; Clastre, M.; Courdavault, V.; O'Connor, S. E.: De novo production of the plant-derived alkaloid strictosidine in yeast. Proceedings of the National Academy of Sciences of the United States of America 112 (11), pp. 3205 - 3210 (2015)

Brown, S.; O'Connor, S. E.: Halogenase engineering for the generation of new natural product analogues. Chembiochem 16 (15), pp. 2129 - 2135 (2015)

de Bernonville, T. D.; Foureau, E.; Parage, C.; Lanoue, A.; Clastre, M.; Londono, M. A.; Oudin, A.; Houille, B.; Papon, N.; Besseau, S. et al.; Glevarec, G.; Atehortua, L.; Giglioli-Guivarc'h, N.; St-Pierre, B.; De Luca, V.; O'Connor, S. E.; Courdavault, V.: Characterization of a second secologanin synthase isoform producing both secologanin and secoxyloganin allows enhanced de novo assembly of a Catharanthus roseus transcriptome. BMC Genomics 16, 619 (2015)

Jakubczyk, D.; Caputi, L.; Hatsch, A.; Nielsen, C. A. F.; Diefenbacher, M.; Klein, J.; Molt, A.; Schroeder, H.; Cheng, J. Z.; Naesby, M. et al.; O'Connor, S. E.: Discovery and reconstitution of the cycloclavine biosynthetic pathwa—enzymatic formation of a cyclopropyl group. Angewandte Chemie International Edition 54 (17), pp. 5117 - 5121 (2015)

Kellner, F.; Geu-Flores, F.; Sherden, N. H.; Brown, S.; Foureau, E.; Courdavault, V.; O'Connor, S. E.: Discovery of a P450-catalyzed step in vindoline biosynthesis: a link between the aspidosperma and eburnamine alkaloids. Chemical Communications 51 (36), pp. 7626 - 7628 (2015)

Kellner, F.; Kim, J.; Clavijo, B. J.; Hamilton, J. P.; Childs, K. L.; Vaillancourt, B.; Cepela, J.; Habermann, M.; Steuernagel, B.; Clissold, L. et al.; McLay, K.; Buell, C. R.; O'Connor, S. E.: Genome-guided investigation of plant natural product biosynthesis. The Plant Journal 82 (4), pp. 680 - 692 (2015)

Munkert, J.; Pollier, J.; Miettinen, K.; Van Moerkercke, A.; Payne, R.; Mueller-Uri, F.; Burlat, V.; O'Connor, S. E.; Memelink, J.; Kreis, W. et al.; Goossens, A.: Iridoid synthase activity is common among the plant progesterone 5β-reductase family. Molecular Plant 8 (1), pp. 136 - 152 (2015)