Publications

Grzech, D.; Hong, B.; Caputi, L.; Sonawane, P. D.; O’Connor, S. E.: Engineering the biosynthesis of late-stage vinblastine precursors precondylocarpine acetate, catharanthine, tabersonine in Nicotiana benthamiana. ACS Synthetic Biology 12 (1), pp. 27 - 34 (2023)

Jiang, N.-J.; Chang, H.; Weisflog, J.; Eberl, F.; Veit, D.; Weniger, K.; Hansson, B. S.; Knaden, M.: Ozone exposure disrupts insect sexual communication. Nature Communications 14, 1186 (2023)

Kandasamy, D.; Zaman, R.; Nakamura, Y.; Tao, Z.; Hartmann, H.; Andersson, M. N.; Hammerbacher, A.; Gershenzon, J.: Conifer-killing bark beetles locate fungal symbionts by detecting volatile fungal metabolites of host tree resin monoterpenes. PLoS Biology 21 (2), e3001887 (2023)

Laforest, L. C.; Kuntz, M. A.; Kanumuri, S. R. R.; Mukhopadhyay, S.; Sharma, A.; O’Connor, S. E.; McCurdy, C. R.; Nadakuduti, a. S. S.: Metabolite and molecular characterization of Mitragyna speciosa identifies developmental and genotypic effects on monoterpene indole and oxindole alkaloid composition. Journal of Natural Products (2023)

Nosenko, T.; Zimmer, I.; Ghirardo, A.; Köllner, T. G.; Weber, B.; Polle, A.; Rosenkranz, M.; Schnitzler, J.-P.: Predicting functions of putative fungal sesquiterpene synthase genes based on multiomics data analysis. Fungal Genetics and Biology 165, 103779 (2023)

Petrén, H.; Köllner, T. G.; Junker, R. R.: Quantifying chemodiversity considering biochemical and structural properties of compounds with the R package chemodiv. New Phytologist 237 (6), pp. 2478 - 2492 (2023)

Schotte, C.; Jiang, Y.; Grzech, D.; Dang, T.-T. T.; Laforest, L. C.; León, F.; Mottinelli, M.; Nadakuduti, S. S.; McCurdy, C. R.; O’Connor, S. E.: Directed biosynthesis of mitragynine stereoisomers. Journal of the American Chemical Society 145 (9), pp. 4957 - 4963 (2023)

Boccia, M.; Grzech, D.; Lopes, A. A.; O’Connor, S. E.; Caputi, L.: Directed biosynthesis of new to nature alkaloids in a heterologous Nicotiana benthamiana expression host. Frontiers in Plant Science 13, 919443 (2022)

Colinas, M.; Fitzpatrick, T. B.: Coenzymes and the primary and specialized metabolism interface. Current Opinion in Plant Biology 66, 102170 (2022)

Cuello, C.; Stander, E. A.; Jansen, H. J.; Dugé De Bernonville, T.; Lanoue, A.; Giglioli-Guivarch, N.; Papon, N.; Dirks, R. P.; Jensen, M. K.; O’Connor, S. E. et al.; Bessau, S.; Courdavault, V.: Genome assembly of the medicinal plant Voacanga thouarsii. Genome Biology and Evolution 14 (11), evac158 (2022)

DeMars, M.; Nakamura, Y.; Kamileen, M. O.; Sanders, J. N.; Paetz, C.; Houk, K. N.; O’Connor, S. E.: Mechanism and evolution of [4+2] cyclases in monoterpene indole alkaloid biosynthesis. Faseb Journal 36 (S1) (2022)

Dudley, Q. M.; Jo, S.; Serna Guerrero, D. A.; Chhetry, M.; Smedley, M. A.; Harwood, W. A.; Sherden, N. H.; O’Connor, S. E.; Caputi, L.; Patron, N. J.: Reconstitution of monoterpene indole alkaloid biosynthesis in genome engineered Nicotiana benthamiana. Communications Biology 5, 949 (2022)

Gordon, H.; Fellenberg, C.; Lackus, N.; Archinuk, F.; Sproule, A.; Nakamura, Y.; Köllner, T. G.; Gershenzon, J.; Overy, D. P.; Constabel, C. P.: CRISPR/Cas9 disruption of UGT71L1 in poplar connects salicinoid and salicylic acid metabolism and alters growth and morphology. The Plant Cell 34 (8), pp. 2925 - 2947 (2022)

Hernández-Lozada, N. J.; Hong, B.; Wood, J. C.; Caputi, L.; Basquin, J.; Chuang, L.; Kunert, M.; Rodriguez Lopez, C. E.; Langley, C.; Zhao, D. et al.; Buell, C. R.; Lichman, B. R.; O’Connor, S. E.: Biocatalytic routes to stereo-divergent iridoids. Nature Communications 13, 4718 (2022)

Hong, B.; Grzech, D.; Caputi, L.; Sonawane, P. D.; Rodriguez Lopez, C. E.; Kamileen, M. O.; Hernández-Lozada, N. J.; O’Connor, S. E.: Biosynthesis of strychnine. Nature 607, pp. 617 - 622 (2022)

Kamileen, M. O.; DeMars II, M. D.; Hong, B.; Nakamura, Y.; Paetz, C.; Lichman, B. R.; Sonawane, P. D.; Caputi, L.; O’Connor, S. E.: Recycling upstream redox enzymes expands the regioselectivity of cycloaddition in Pseudo-Aspidosperma alkaloid biosynthesis. Journal of the American Chemical Society 144 (42), pp. 19673 - 19579 (2022)

Köllner, T. G.; David, A.; Luck, K.; Beran, F.; Kunert, G.; Zhou, J.-J.; Caputi, L.; O’Connor, S. E.: Biosynthesis of iridoid sex pheromones in aphids. Proceedings of the National Academy of Sciences of the United States of America 119 (42), e2211254119 (2022)

Koudounas, K.; Guirimand, G.; Hoyos, L. F. R.; Carqueijeiro, I.; Cruz, P. L.; Stander, E.; Kulagina, N.; Perrin, J.; Oudin, A.; Besseau, S. et al.; Lanoue, A.; Atehortùa, L.; St-Pierre, B.; Giglioli-Guivarc’h, N.; Papon, N.; O’Connor, S. E.; Courdavault, V.: Tonoplast and peroxisome targeting of gamma-tocopherol N-methyltransferase homologs involved in the synthesis of monoterpene indole alkaloids. Plant and Cell Physiology 63 (2), pcab160, pp. 200 - 216 (2022)

Kulagina, N.; Méteignier, L.-V.; Papon, N.; O’Connor, S. E.; Courdavault, V.: More than a Catharanthus plant: A multicellular and pluri-organelle alkaloid-producing factory. Current Opinion in Plant Biology 67, 102200 (2022)

Langley, C.; Tatsis, E. E.; Hong, B.; Nakamura, Y.; Paetz, C.; Stevenson, C. E. M.; Basquin, J.; Lawson, D. M.; Caputi, L.; O’Connor, S. E.: Expansion of the catalytic repertoire of alcohol dehydrogenases in plant metabolism. Angewandte Chemie, International Edition in English 61 (48), e202210934 (2022)