Publications of Sarah E. O’Connor

Hong, B.; Grzech, D.; Caputi, L.; Sonawane, P. D.; Rodriguez Lopez, C. E.; Kamileen, M. O.; Hernández-Lozada, N. J.; O’Connor, S. E.: Biosynthesis of strychnine. Nature 607, pp. 617 - 622 (2022)

Hernández Lozada, N. J.; Hong, B.; Wood, J. C.; Caputi, L.; Basquin, J.; Chuang, L.; Kunert, M.; Rodriguez Lopez, C. E.; Langley, C.; Zhao, D. et al.; Buell, C. R.; Lichman, B. R.; O’Connor, S. E.: A biocatalytic toolkit for the control of iridoid stereochemistry. Nature Communications (accepted)

Langley, C.; Tatsis, E. E.; Hong, B.; Nakamura, Y.; Paetz, C.; Stevenson, C. E. M.; Basquin, J.; Lawson, D. M.; Caputi, L.; O’Connor, S. E.: Expansion of the catalytic repertoire of alcohol dehydrogenases in plant metabolism. bioRxiv (2022)

Boccia, M.; Grzech, D.; Lopes, A. A.; O’Connor, S. E.; Caputi, L.: Directed biosynthesis of new to nature alkaloids in a heterologous Nicotiana benthamiana expression host. Frontiers in Plant Science 13, 919443 (2022)

Kulagina, N.; Méteignier, L.-V.; Papon, N.; O’Connor, S. E.; Courdavault, V.: More than a Catharanthus plant: A multicellular and pluri-organelle alkaloid-producing factory. Current Opinion in Plant Biology 67, 102200 (2022)

DeMars, M.; Nakamura, Y.; Kamileen, M. O.; Sanders, J. N.; Paetz, C.; Houk, K. N.; O’Connor, S. E.: Mechanism and evolution of [4+2] cyclases in monoterpene indole alkaloid biosynthesis. Faseb Journal 36 (S1) (2022)

Rodriguez Lopez, C. E.; Jiang, Y.; Kamileen, M. O.; Lichman, B. R.; Hong, B.; Vaillancourt, B.; Buell, C. R.; O’Connor, S. E.: Phylogeny-aware chemoinformatic analysis of chemical diversity in Lamiaceae enables iridoid pathway assembly and discovery of aucubin synthase. Molecular Biology and Evolution 39 (4), msac057 (2022)

Koudounas, K.; Guirimand, G.; Hoyos, L. F. R.; Carqueijeiro, I.; Cruz, P. L.; Stander, E.; Kulagina, N.; Perrin, J.; Oudin, A.; Besseau, S. et al.; Lanoue, A.; Atehortùa, L.; St-Pierre, B.; Giglioli-Guivarc’h, N.; Papon, N.; O’Connor, S. E.; Courdavault, V.: Tonoplast and peroxisome targeting of gamma-tocopherol N-methyltransferase homologs involved in the synthesis of monoterpene indole alkaloids. Plant and Cell Physiology 63 (2), pcab160, pp. 200 - 216 (2022)

Courdavault, V.; O’Connor, S. E.; Jensen, M. K.; Papon, N.: Metabolic engineering for plant natural products biosynthesis: new procedures, concrete achievements and remaining limits. Natural Product Reports 38 (12), pp. 2145 - 2153 (2021)

Yamamoto, K.; Grzech, D.; Koudounas, K.; Stander, E. A.; Caputi, L.; Mimura, T.; Courdavault, V.; O’Connor, S. E.: Improved virus-induced gene silencing allows discovery of a serpentine synthase gene in Catharanthus roseus. Plant Physiology 187 (2), pp. 846 - 857 (2021)

Bat-Erdene, U.; Billingsley, J. M.; Turner, W. C.; Lichman, B. R.; Ippoliti, F. M.; Garg, N. K.; O’Connor, S. E.; Tang, a. Y.: Cell-free total biosynthesis of plant terpene natural products using an orthogonal cofactor regeneration system. ACS Catalysis 11 (15), pp. 9898 - 9903 (2021)

Brose, J.; Lau, K. H.; Dang, T. T. T.; Hamilton, J. P.; do Vale Martins, L.; Hamberger, B.; Hamberger, B.; Jiang, J.; O’Connor, S. E.; Buell, C. R.: The Mitragyna speciosa (Kratom) Genome: a resource for data-mining potent pharmaceuticals that impact human health. G3: Genes, Genomes, Genetics 11 (4), jkab058 (2021)

Carqueijeiro, I.; Koudounas, K.; de Bernonville, T. D.; Sepúlveda, L. J.; Mosquera, A.; Bomzan, D. P.; Oudin, A.; Lanoue, A.; Besseau, S.; Cruz, P. L. et al.; Kulagina, N.; Stander, E. A.; Eymieux, S.; Burlaud-Gaillard, J.; Blanchard, E.; Clastre, M.; Atehortùa, L.; St-Pierre, B.; Giglioli-Guivarc’h, N.; Papon, N.; Nagegowda, D. A.; O’Connor, S. E.; Courdavault, V.: Alternative splicing creates a pseudo-strictosidine beta-D-glucosidase modulating alkaloid synthesis in Catharanthus roseus. Plant Physiology 185 (3), pp. 836 - 856 (2021)

Trenti, F.; Yamamoto, K.; Hong, B.; Paetz, C.; Nakamura, Y.; O’Connor, S. E.: Early and late steps of quinine biosynthesis. Organic Letters 23 (5), pp. 1793 - 1797 (2021)

Rodríguez‐López, C. E.; Hong, B.; Paetz, C.; Nakamura, Y.; Koudounas, K.; Passeri, V.; Baldoni, L.; Alagna, F.; Calderini, O.; O’Connor, S. E.: Two bi-functional cytochrome P450 CYP72 enzymes from olive (Olea europaea) catalyze the oxidative C-C bond cleavage in the biosynthesis of secoxy-iridoids – flavor and quality determinants in olive oil. New Phytologist 229 (4), pp. 2288 - 2301 (2021)

O’Connor, S. E.: Symbionts, peptides, and (no) Iron: How ants defend their fungal crop. ACS Central Science 7 (2), pp. 225 - 227 (2021)

Stander, E. A.; Sepúlveda, L. J.; de Bernonville, T. D.; Carqueijeiro, I.; Koudounas, K.; Cruz, P. L.; Besseau, S.; Lanoue, A.; Papon, N.; Giglioli-Guivarc’h, N. et al.; Dirks, R.; O’Connor, S. E.; Atehortùa, L.; Oudin, A.; Courdavault, V.: Identifying genes involved in alkaloid biosynthesis in Vinca minor through transcriptomics and gene co-expression analysis. Biomolecules 10 (12), 1595 (2020)

Davis, K.; Gkotsi, D. S.; Smith, D. R. M.; Goss, R. J. M.; Caputi, L.; O’Connor, S. E.: Nicotiana benthamiana as a transient expression host to produce auxin analogs. Frontiers in Plant Science 11, 581675 (2020)

de Bernonville, T. D.; Maury, S.; Delaunay, A.; Daviaud, C.; Chaparro, C.; Tost, J.; O’Connor, S. E.; Courdavault, V.: Developmental methylome of the medicinal plant Catharanthus roseus unravels the tissue-specific control of the monoterpene indole alkaloid pathway by DNA methylation. International Journal of Molecular Sciences 21 (17), 6028 (2020)

Nguyen, T.-D.; O’Connor, S. E.: The progesterone 5 beta-reductase/iridoid synthase family: A catalytic reservoir for specialized metabolism across land plants. ACS Chemical Biology 15 (7), pp. 1780 - 1787 (2020)