Publications of Sarah E. O'Connor

Stavrinides, A.; Tatsis, E. C.; Foureau, E.; Caputi, L.; Kellner, F.; Courdavault, V.; O'Connor, S. E.: Unlocking the diversity of alkaloids in Catharanthus roseus: nuclear localization suggests metabolic channeling in secondary metabolism. Chemistry & Biology 22 (3), pp. 336 - 341 (2015)

Van Moerkercke, A.; Steensma, P.; Schweizer, D.; Pollier, J.; Gariboldi, I.; Payne, A.; Bossche, R. V.; Miettinen, K.; Espoz, J.; Purnama, P. C. et al.; Kellner, F.; Seppänen-Laakso, T.; O'Connor, S. E.; Rischer, H.; Memelink, J.; Goossens, A.: The bHLH transcription factor BIS1 controls the iridoid branch of the monoterpenoid indole alkaloid pathway in Catharanthus roseus. Proceedings of the National Academy of Sciences of the United States of America 112 (26), pp. 8130 - 8135 (2015)

Jakubczyk, D.; Cheng, J. Z.; O'Connor, S. E.: Biosynthesis of the ergot alkaloids. Natural Product Reports 31 (10), pp. 1328 - 1338 (2014)

Lindner, S.; Geu-Flores, F.; Braese, S.; Sherden, N. H.; O'Connor, S. E.: Conversion of substrate analogs suggests a Michael cyclization in iridoid biosynthesis. Chemistry & Biology 21 (11), pp. 1452 - 1456 (2014)

Nielsen, C. A. F.; Folly, C.; Hatsch, A.; Molt, A.; Schroeder, H.; O'Connor, S. E.; Naesby, M.: The important ergot alkaloid intermediate chanoclavine-I produced in the yeast Saccharomyces cerevisiae by the combined action of EasC and EasE from Aspergillus japonicus. Microbial Cell Factories 13, 95 (2014)

O'Connor, S. E.; Brutnell, T. P.: Editorial overview: Growing the future: synthetic biology in plants. Current Opinion in Plant Biology 19, pp. IV - V (2014)

Besseau, S.; Kellner, F.; Lanoue, A.; Thamm, A. M.; Salim, V.; Schneider, B.; Geu-Flores, F.; Höfer, R.; Guirimand, G.; Guihur, A. et al.; Oudin, A.; Glevarec, G.; Foureau, E.; Papon, N.; Clastre, M.; Giglioli-Guivarc’h, N.; St-Pierre, B.; Werck-Reichhart, D.; Burlat, V.; Luca, V. D.; O'Connor, S. E.; Courdavault, V.: A pair of tabersonine 16-hydroxylases initiates the synthesis of vindoline in an organ dependent manner in Catharanthus roseus. Plant Physiology 163 (4), pp. 1792 - 1803 (2013)

Glenn, W. S.; Runguphan, W.; O'Connor, S. E.: Recent progress in the metabolic engineering of alkaloids in plant systems. Current Opinion in Biotechnology 24 (2), pp. 354 - 365 (2013)

Runguphan, W.; O'Connor, S. E.: Diversification of monoterpene indole alkaloid analogs through cross-coupling. Organic Letters 15 (11), pp. 2850 - 2853 (2013)

DellaPenna, D.; O'Connor, S. E.: Plant gene clusters and opiates. Science 336 (6089), pp. 1648 - 1649 (2012)

Geu-Flores, F.; Sherden, N. H.; Courdavault, V.; Burlat, V.; Glenn, W. S.; Wu, C.; Nims, E.; Cui, Y.; O'Connor, S. E.: An alternative route to cyclic terpenes by reductive cyclization in iridoid biosynthesis. Nature 492 (7427), pp. 138 - 142 (2012)

Gongora-Castillo, E.; Childs, K. L.; Fedewa, G.; Hamilton, J. P.; Liscombe, D. K.; Magallanes-Lundback, M.; Mandadi, K. K.; Nims, E.; Runguphan, W.; Vaillancourt, B. et al.; Varbanova-Herde, M.; DellaPenna, D.; McKnight, T. D.; O'Connor, S. E.; Buell, C. R.: Development of transcriptomic resources for interrogating the biosynthesis of monoterpene indole alkaloids in medicinal plant species. PLoS One 7 (12), e52506 (2012)

Panjikar, S.; Stoeckigt, J.; O'Connor, S. E.; Warzecha, H.: The impact of structural biology on alkaloid biosynthesis research. Natural Product Reports 29 (10), pp. 1176 - 1200 (2012)

Ruff, B. M.; Braese, S.; O'Connor, S. E.: Biocatalytic production of tetrahydroisoquinolines. Tetrahedron Letters 53 (9), pp. 1071 - 1074 (2012)

Runguphan, W.; Glenn, W. S.; O'Connor, S. E.: Redesign of a dioxygenase in morphine biosynthesis. Chemistry & Biology 19 (6), pp. 674 - 678 (2012)

Giddings, L.-A.; Liscombe, D. K.; Hamilton, J. P.; Childs, K. L.; DellaPenna, D.; Buell, C. R.; O'Connor, S. E.: A stereoselective hydroxylation step of alkaloid biosynthesis by a unique cytochrome P450 in Catharanthus roseus. The Journal of Biological Chemistry 286 (19), pp. 16751 - 16757 (2011)

Glenn, W. S.; Nims, E.; O'Connor, S. E.: Reengineering a tryptophan halogenase to preferentially chlorinate a direct alkaloid precursor. Journal of the American Chemical Society 133 (48), pp. 19346 - 19349 (2011)

Goetz, K. E.; Coyle, C. M.; Cheng, J. Z.; O'Connor, S. E.; Panaccione, D. G.: Ergot cluster-encoded catalase is required for synthesis of chanoclavine-I in Aspergillus fumigatus. Current Genetics 57 (3), pp. 201 - 211 (2011)

Hicks, M. A.; Barber II, A. E.; Giddings, L.-A.; Caldwell, J.; O'Connor, S. E.; Babbitt, P. C.: The evolution of function in strictosidine synthase-like proteins. Proteins: Structure, Function, and Bioinformatics 79 (11), pp. 3082 - 3098 (2011)

Liscombe, D. K.; O'Connor, S. E.: A virus-induced gene silencing approach to understanding alkaloid metabolism in Catharanthus roseus. Phytochemistry 72 (16), pp. 1969 - 1977 (2011)