Publications of Sarah E. O'Connor

Ruff, B. M.; Braese, S.; O'Connor, S. E.: Biocatalytic production of tetrahydroisoquinolines. Tetrahedron Letters 53 (9), pp. 1071 - 1074 (2012)

Runguphan, W.; Glenn, W. S.; O'Connor, S. E.: Redesign of a dioxygenase in morphine biosynthesis. Chemistry & Biology 19 (6), pp. 674 - 678 (2012)

Giddings, L.-A.; Liscombe, D. K.; Hamilton, J. P.; Childs, K. L.; DellaPenna, D.; Buell, C. R.; O'Connor, S. E.: A stereoselective hydroxylation step of alkaloid biosynthesis by a unique cytochrome P450 in Catharanthus roseus. The Journal of Biological Chemistry 286 (19), pp. 16751 - 16757 (2011)

Glenn, W. S.; Nims, E.; O'Connor, S. E.: Reengineering a tryptophan halogenase to preferentially chlorinate a direct alkaloid precursor. Journal of the American Chemical Society 133 (48), pp. 19346 - 19349 (2011)

Goetz, K. E.; Coyle, C. M.; Cheng, J. Z.; O'Connor, S. E.; Panaccione, D. G.: Ergot cluster-encoded catalase is required for synthesis of chanoclavine-I in Aspergillus fumigatus. Current Genetics 57 (3), pp. 201 - 211 (2011)

Hicks, M. A.; Barber II, A. E.; Giddings, L.-A.; Caldwell, J.; O'Connor, S. E.; Babbitt, P. C.: The evolution of function in strictosidine synthase-like proteins. Proteins: Structure, Function, and Bioinformatics 79 (11), pp. 3082 - 3098 (2011)

Liscombe, D. K.; O'Connor, S. E.: A virus-induced gene silencing approach to understanding alkaloid metabolism in Catharanthus roseus. Phytochemistry 72 (16), pp. 1969 - 1977 (2011)

Liscombe, D. K.; Usera, A. R.; O'Connor, S. E.: Homolog of tocopherol C methyltransferases catalyzes N methylation in anticancer alkaloid biosynthesis. Proceedings of the National Academy of Sciences of the United States of America 107 (44), pp. 18793 - 18798 (2010)

Bernhardt, P.; Usera, A. R.; O'Connor, S. E.: Biocatalytic asymmetric formation of tetrahydro-beta-carbolines. Tetrahedron Letters 51 (33), pp. 4400 - 4402 (2010)

Cheng, J. Z.; Coyle, C. M.; Panaccione, D. G.; O'Connor, S. E.: Controlling a structural branch point in ergot alkaloid biosynthesis. Journal of the American Chemical Society 132 (37), pp. 12835 - 12837 (2010)

Cheng, J. Z.; Coyle, C. M.; Panaccione, D. G.; O'Connor, S. E.: A role for old yellow enzyme in ergot alkaloid biosynthesis. The Journal of Physical Chemistry B 132 (6), pp. 1776 - 1777 (2010)

Coyle, C. M.; Cheng, J. Z.; O'Connor, S. E.; Panaccione, D. G.: An old yellow enzyme gene controls the branch point between Aspergillus fumigatus and Claviceps purpurea ergot alkaloid pathways. Applied and Environmental Microbiology 76 (12), pp. 3898 - 3903 (2010)

Runguphan, W.; Qu, X.; O'Connor, S. E.: Integrating carbon-halogen bond formation into medicinal plant metabolism. Nature 468, pp. 461 - 464 (2010)

Runguphan, W.; Maresh, J. J.; O'Connor, S. E.: Silencing of tryptamine biosynthesis for production of nonnatural alkaloids in plant culture. Proceedings of the National Academy of Sciences of the United States of America 106 (33), pp. 13673 - 13678 (2009)

Bernhardt, P.; O'Connor, S. E.: Synthesis and biochemical evaluation of des-vinyl secologanin aglycones with alternate stereochemistry. Tetrahedron Letters 50 (51), pp. 7118 - 7120 (2009)

Bernhardt, P.; O'Connor, S. E.: Opportunities for enzyme engineering in natural product biosynthesis. Current Opinion in Chemical Biology 13 (1), pp. 35 - 42 (2009)

Bernhardt, P.; Yerkes, N.; O'Connor, S. E.: Bypassing stereoselectivity in the early steps of alkaloid biosynthesis. Organic & Biomolecular Chemistry 7 (20), pp. 4166 - 4168 (2009)

Friedrich, A.; Brase, S.; O'Connor, S. E.: Synthesis of 4-, 5-, 6-, and 7-azidotryptamines. Tetrahedron Letters 50 (1), pp. 75 - 76 (2009)

Lee, H.-Y.; Yerkes, N.; O'Connor, S. E.: Aza-tryptamine substrates in monoterpene indole alkaloid biosynthesis. Chemistry & Biology 16 (12), pp. 1225 - 1229 (2009)

Leonard, E.; Runguphan, W.; O'Connor, S. E.; Prather, K. J.: Opportunities in metabolic engineering to facilitate scalable alkaloid production. Nature Chemical Biology 5 (5), pp. 292 - 300 (2009)