Dr. Yannick Pauchet

   Department of Entomology
   Molecular Biology of the Insect Digestive System
 Phone:+49 (0)3641 57 1507Max Planck Institute for Chemical Ecology
 Fax:+49 (0)3641 57 1502Hans-Knöll-Straße 8
  emailD-07745 Jena

 Research  CV  Publications  Presentations  Awards  help    to staff list 
1Haeger, W., Henning, J., Heckel, D. G., Pauchet, Y., Kirsch, R. (2020). Direct evidence for a new mode of plant defense against insects via a novel polygalacturonase-inhibiting protein expression strategy. Journal of Biological Chemistry, 295(33), 11833-11844. doi:10.1074/jbc.RA120.014027. [HEC460] OPEN ACCESS gold MPG.PuRE
2Kirsch, R., Vurmaz, E., Schaefer, C., Eberl, F., Sporer, T., Haeger, W., Pauchet, Y. (2020). Plants use identical inhibitors to protect their cell wall pectin against microbes and insects. Ecology and Evolution, 10(8), 3814-3824. doi:10.1002/ece3.6180. [HEC451] OPEN ACCESS gold MPG.PuRE
3Pauchet, Y., Ruprecht, C., Pfrengle, F. (2020). Analyzing the substrate specificity of a class of long-horned-beetle-derived, xylanases by using synthetic arabinoxylan oligo- and polysaccharides. ChemBioChem: A European Journal of Chemical Biology, 21(10), 1517-1525. doi:10.1002/cbic.201900687. [HEC446] OPEN ACCESS gold MPG.PuRE
4Reis, F., Kirsch, R., Pauchet, Y., Bauer, E., Bilz, L. C., Fukumori, K., Fukatsu, T., Kölsch, G., Kaltenpoth, M. (2020). Bacterial symbionts support larval sap feeding and adult folivory in (semi-)aquatic reed beetles. Nature Communications, 11(1): 2964. doi:10.1038/s41467-020-16687-7. [HEC459] OPEN ACCESS gold MPG.PuRE
5Salem, H., Kirsch, R., Pauchet, Y., Berasategui, A., Fukumori, K., Moriyama, M., Cripps, M., Windsor, D., Fukatsu, T., Gerardo, N. M. (2020). Symbiont digestive range reflects host plant breadth in herbivorous beetles. Current Biology, 30(15), 2875-2886. doi:10.1016/j.cub.2020.05.043. [HEC458] MPG.PuRE
6Shelomi, M., Wipfler, B., Zhou, X., Pauchet, Y. (2020). Multifunctional cellulase enzymes are ancestral in Polyneoptera. Insect Molecular Biology, 29(1), 124-135. doi:10.1111/imb.12614. [HEC438] MPG.PuRE
1Busch, A., Danchin, E. G. J., Pauchet, Y. (2019). Functional diversification of horizontally acquired glycoside hydrolase family 45 (GH45) proteins in Phytophaga beetles. BMC Evolutionary Biology, 19: 100. doi:10.1186/s12862-019-1429-9. [HEC419] OPEN ACCESS gold MPG.PuRE
2Fu, N., Yang, Z.-l., Pauchet, Y., Paetz, C., Brandt, W., Boland, W., Burse, A. (2019). A cytochrome P450 from juvenile mustard leaf beetles hydroxylates geraniol, a key step in iridoid biosynthesis. Insect Biochemistry and Molecular Biology, 113: 103212. doi:10.1016/j.ibmb.2019.103212. preprint available [BOL713] MPG.PuRE
3Kirsch, R., Kunert, G., Vogel, H., Pauchet, Y. (2019). Pectin digestion in herbivorous beetles: Impact of pseudoenzymes exceeds that of their active counterparts. Frontiers in Physiology, 10: 685. doi:10.3389/fphys.2019.00685. [HEC402] OPEN ACCESS gold MPG.PuRE
4Kuwar, S., Pauchet, Y., Heckel, D. G. (2019). Effects of class-specific, synthetic, and natural proteinase inhibitors on life-history traits of the cotton bollworm Helicoverpa armigera. Archives of Insect Biochemistry and Physiology, 103(4): e21647. doi:10.1002/arch.21647. [HEC444] OPEN ACCESS gold MPG.PuRE
1Busch, A., Kunert, G., Wielsch, N., Pauchet, Y. (2018). Cellulose degradation in Gastrophysa viridula (Coleoptera: Chrysomelidae): functional characterization of two CAZymes belonging to glycoside hydrolase family 45 reveals a novel enzymatic activity. Insect Molecular Biology, 27(5), 633-650. doi:10.1111/imb.12500. [HEC393] MPG.PuRE
2Schoville, S. D., Chen, Y. H., Andersson, M. N., Benoit, J. B., Bhandari, A., Bowsher, J. H., Brevik, K., Cappelle, K., Chen, M.-J.-M., Childers, A. K., Childers, C., Christiaens, O., Clements, J., Elpidina, E. N., Engsontia, P., Friedrich, M., García-Robles, I., Gibbs, R. A., Goswami, C., Grapputo, A., Gruden, K., Grynberg, M., Henrissat, B., Jennings, E. C., Jones, J. W., Kalsi, M., Khan, S. A., Kumar, A., Li, F., Lombard, V., Ma, X., Martynov, A., Miller, N. J., Mitchell, R. F., Munoz-Torres, M., Muszewska, A., Oppert, B., Palli, S. R., Panfilio, K. A., Pauchet, Y., Perkin, L. C., Petek, M., Poelchau, M. F., Record, É., Rinehart, J. P., Robertson, H. M., Rosendale, A. J., Ruiz-Arroyo, V. M., Smagghe, G., Szendrei, Z., Szuter, E. M., Thomas, G. W., Torson, A. S., Jentzsch, I. M. V., Weirauch, M. T., Yates, A. D., Yocum, G. D., Yoon, J.-S., Richards, S. (2018). A model species for agricultural pest genomics: the genome of the Colorado potato beetle, Leptinotarsa decemlineata (Coleoptera: Chrysomelidae). Scientific Reports, 8: 1931. doi:10.1038/s41598-018-20154-1. [HEC380] OPEN ACCESS gold MPG.PuRE
1Busch, A., Kunert, G., Heckel, D. G., Pauchet, Y. (2017). Evolution and functional characterization of CAZymes belonging to subfamily 10 of glycoside hydrolase family 5 (GH5_10) in two species of phytophagous beetles. PLoS One, 12(8): e0184305. doi:10.1371/journal.pone.0184305. [HEC376] OPEN ACCESS gold MPG.PuRE
1Barthel, A., Vogel, H., Pauchet, Y., Pauls, G., Kunert, G., Groot, A. T., Boland, W., Heckel, D. G., Heidel-Fischer, H. M. (2016). Immune modulation enables a specialist insect to benefit from antibacterial withanolides in its host plant. Nature Communications, 7: 12530. doi:10.1038/ncomms12530. [HEC346] OPEN ACCESS gold MPG.PuRE
2Bretschneider, A., Heckel, D. G., Pauchet, Y. (2016). Three toxins, two receptors, one mechanism: Mode of action of Cry1A toxins from Bacillus thuringiensis in Heliothis virescens. Insect Biochemistry and Molecular Biology, 76, 109-117. doi:10.1016/j.ibmb.2016.07.008. [HEC343] MPG.PuRE
3Kanost, M. R., Arrese, E. L., Cao, X., Chen, Y.-R., Chellapilla, S., Goldsmith, M., Grosse-Wilde, E., Heckel, D. G., Herndon, N., Jiang, H., Papanicolaou, A., Qu, J., Soulages, J. L., Vogel, H., Walters, J., Waterhouse, R. M., Ahn, S.-J., Almeida, F. C., An, C., Aqrawi, P., Bretschneider, A., Bryant, W. B., Bucks, S., Chao, H., Chevignon, G., Christen, J. M., Clarke, D. F., Dittmer, N. T., Ferguson, L. C., Garavelou, S., Gordon, K. H., Gunaratna, R. T., Han, Y., Hauser, F., He, Y., Heidel-Fischer, H. M., Hirsh, A., Hu, Y., Jiang, H., Kalra, D., Klinner, C., König, C., Kovar, C., Kroll, A. R., Kuwar, S., Lee, S. L., Lehman, R., Li, K., Li, Z., Liang, H., Lovelace, S., Lu, Z., Mansfield, J. H., McCulloch, K. J., Mathew, T., Morton, B., Muzny, D. M., Neunemann, D., Ongeri, F., Pauchet, Y., Pu, L.-L., Pyrousis, I., Rao, X.-J., Redding, A., Roesel, C., Sanchez-Gracia, A., Schaack, S., Shukla, A., Tetreau, G., Wang, Y., Xiong, G.-H., Traut, W., Walsh, T. K., Worley, K. C., Wu, D., Wu, W., Wu, Y.-Q., Zhang, X., Zou, Z., Zucker, H., Briscoe, A. D., Burmester, T., Clem, R., Feyereisen, R., Grimmelikhuijzen, C. J., Hamodrakas, S. J., Hansson, B. S., Huguet, E., Jermiin, L. S., Lan, Q., Lehman, H. K., Lorenzen, M., Merzendorfer, H., Michalopoulos, I., Morton, D. B., Muthukrishnan, S., Oakeshott, J. G., Palmer, W., Park, Y., Passarelli, A. L., Rozas, J., Schwartz, L. M., Smith, W., Southgate, A., Vilcinskas, A., Vogt, R., Wang, P., Werren, J., Yu, X.-Q., Zhou, J.-J., Brown, S. J., Scherer, S. E., Richards, S., Blissard, G. W. (2016). Multifaceted biological insights from a draft genome sequence of the tobacco hornworm moth, Manduca sexta. Insect Biochemistry and Molecular Biology, 76, 118-147. doi:10.1016/j.ibmb.2016.07.005. [HEC342] MPG.PuRE
4Kirsch, R., Heckel, D. G., Pauchet, Y. (2016). How the rice weevil breaks down the pectin network: Enzymatic synergism and sub-functionalization. Insect Biochemistry and Molecular Biology, 71, 72-82. doi:10.1016/j.ibmb.2016.02.007. [HEC324] MPG.PuRE
5McKenna, D. D., Scully, E. D., Pauchet, Y., Hoover, K., Kirsch, R., Geib, S. M., Mitchell, R. F., Waterhouse, R. M., Ahn, S.-J., Arsala, D., Benoit, J. B., Blackmon, H., Bledsoe, T., Bowsher, J. H., Busch, A., Calla, B., Chao, H., Childers, A. K., Childers, C., Clarke, D. J., Cohen, L., Demuth, J. P., Dinh, H., Doddapaneni, H., Dolan, A., Duan, J. J., Dugan, S., Friedrich, M., Glastad, K. M., Goodisman, M. A. D., Haddad, S., Han, Y., Hughes, D. S. T., Ioannidis, P., Johnston, J. S., Jones, J. W., Kuhn, L. A., Lance, D. R., Lee, C.-Y., Lee, S. L., Lin, H., Lynch, J. A., Moczek, A. P., Murali, S. C., Muzny, D. M., Nelson, D. R., Palli, S. R., Panfilio, K. A., Pers, D., Poelchau, M. F., Quan, H., Qu, J., Ray, A. M., Rinehart, J. P., Robertson, H. M., Roehrdanz, R., Rosendale, A. J., Shin, S., Silva, C., Torson, A. S., Jentzsch, I. M. V., Werren, J. H., Worley, K. C., Yocum, G., Zdobnov, E. M., Gibbs, R. A., Richards, S. (2016). Genome of the Asian longhorned beetle (Anoplophora glabripennis), a globally significant invasive species, reveals key functional and evolutionary innovations at the beetle–plant interface. Genome Biology, 17: 227. doi:10.1186/s13059-016-1088-8. [HEC354] OPEN ACCESS gold MPG.PuRE
6Pauchet, Y., Bretschneider, A., Augustin, S., Heckel, D. G. (2016). A P-glycoprotein is linked to resistance to the Bacillus thuringiensis Cry3Aa toxin in a leaf beetle. Toxins, 8(12): 362. doi:10.3390/toxins8120362. [HEC356] OPEN ACCESS gelb MPG.PuRE
7Shelomi, M., Danchin, E. G. J., Heckel, D. G., Wipfler, B., Bradler, S., Zhou, X., Pauchet, Y. (2016). Horizontal gene transfer of pectinases from bacteria preceded the diversification of stick and leaf insects. Scientific Reports, 6: 26388. doi:10.1038/srep26388. [HEC335] OPEN ACCESS gold MPG.PuRE
8Shelomi, M., Heckel, D. G., Pauchet, Y. (2016). Ancestral gene duplication enabled the evolution of multifunctional cellulases in stick insects (Phasmatodea). Insect Biochemistry and Molecular Biology, 71, 1-11. doi:10.1016/j.ibmb.2016.02.003. [HEC321] MPG.PuRE
9Wybouw, N., Pauchet, Y., Heckel, D. G., Leeuwen, T. V. (2016). Horizontal gene transfer contributes to the evolution of arthropod herbivory. Genome Biology and Evolution, 8(6), 1785-1801. doi:10.1093/gbe/evw119. [HEC336] OPEN ACCESS gold MPG.PuRE
1Badgaa, A., Büchler, R., Wielsch, N., Walde, M., Heintzmann, R., Pauchet, Y., Svatoš, A., Ploss, K., Boland, W. (2015). The green gut: Chlorophyll degradation in the gut of Spodoptora littoralis. Journal of Chemical Ecology, 41, 065-974. doi:10.1007/s10886-015-0636-0. [BOL632] MPG.PuRE
2Kuwar, S., Pauchet, Y., Vogel, H., Heckel, D. G. (2015). Adaptive regulation of digestive serine proteases in the larval midgut of Helicoverpa armigera in response to a plant protease inhibitor. Insect Biochemistry and Molecular Biology, 59, 18-29. doi:10.1016/j.ibmb.2015.01.016. [HEC295] MPG.PuRE
3Pauchet, Y., Wielsch, N., Wilkinson, P. A., Sakaluk, S. K., Svatoš, A., Ffrench-Constant, R. H., Hunt, J., Heckel, D. G. (2015). What’s in the gift? Towards a molecular dissection of nuptial feeding in a cricket. PLoS One, 10(10): e0140191. doi:10.1371/journal.pone.0140191. [HEC313] OPEN ACCESS gold MPG.PuRE
1Beran, F., Pauchet, Y., Kunert, G., Reichelt, M., Wielsch, N., Vogel, H., Reinecke, A., Svatoš, A., Mewis, I., Schmid, D., Ramasamy, S., Ulrichs, C., Hansson, B. S., Gershenzon, J., Heckel, D. G. (2014). Phyllotreta striolata flea beetles utilize host plant defense compounds to create their own glucosinolate-myrosinase system. Proceedings of the National Academy of Sciences of the United States of America, 111(20), 7349-7354. doi:10.1073/pnas.1321781111. [BER001] OPEN ACCESS gold MPG.PuRE
2Buch, F., Pauchet, Y., Rott, M., Mithöfer, A. (2014). Characterization and heterologous expression of a novel PR-1 protein from traps of the carnivorous plant Nepenthes mirabilis. Phytochemistry, 100, 43-50. doi:10.1016/j.phytochem.2014.01.014. [BOL592] MPG.PuRE
3Eyun, S.-i., Wang, H., Pauchet, Y., ffrench-Constant, R. H., Benson, A. K., Valencia-Jimenez, A., Moriyama, E. N., Siegfried, B. D. (2014). Molecular evolution of glycoside hydrolase genes in the western corn rootworm (Diabrotica virgifera virgifera). PLoS One, 9(4): e94052. doi:10.1371/journal.pone.0094052. [HEC277] OPEN ACCESS gold MPG.PuRE
4Kirsch, R., Gramzow, L., Theißen, G., Siegfried, B. D., ffrench-Constant, R. H., Heckel, D. G., Pauchet, Y. (2014). Horizontal gene transfer and functional diversification of plant cell wall degrading polygalacturonases: Key events in the evolution of herbivory in beetles. Insect Biochemistry and Molecular Biology, 52, 33-50. doi:10.1016/j.ibmb.2014.06.008. [HEC279] MPG.PuRE
5Pauchet, Y., Kirsch, R., Giraud, S., Vogel, H., Heckel, D. G. (2014). Identification and characterization of plant cell wall degrading enzymes from three glycoside hydrolase families in the cerambycid beetle Apriona japonica. Insect Biochemistry and Molecular Biology, 49, 1-13. doi:10.1016/j.ibmb.2014.03.004. [HEC270] MPG.PuRE
6Pauchet, Y., Saski, C. A., Feltus, F. A., Luyten, I., Quesneville, H., Heckel, D. G. (2014). Studying the organization of genes encoding plant cell wall degrading enzymes in Chrysomela tremula provides insights into a leaf beetle genome. Insect Molecular Biology, 23(3), 286-300. doi:10.1111/imb.12081. [HEC263] MPG.PuRE
1Pauchet, Y., Heckel, D. G. (2013). The genome of the mustard leaf beetle encodes two active xylanases originally acquired from bacteria through horizontal gene transfer. Proceedings of the Royal Society B: Biological Sciences, 280: 20131021. doi:10.1098/rspb.2013.1021. [HEC243] OPEN ACCESS gold MPG.PuRE
2Smee, M. R., Pauchet, Y., Wilkinson, P., Wee, B., Singer, M. C., Ffrench-Constant, R. H., Hodgson, D. J., Mikheyev, A. S. (2013). Microsatellites for the marsh fritillary butterfly: De novo transcriptome sequencing, and a comparison with amplified fragment length polymorphism (AFLP) markers. PLoS One, 8(1): e54721. doi:10.1371/journal.pone.0054721. [HEC237] OPEN ACCESS gold MPG.PuRE
3Swevers, L., Huvenne, H., Menschaert, G., Kontogiannatos, D., Kourti, A., Pauchet, Y., ffrench-Constant, R., Smagghe, G. (2013). Colorado potato beetle (Coleoptera) gut transcriptome analysis: expression of RNA interference-related genes. Insect Molecular Biology, 22(6), 668-684. doi:10.1111/imb.12054. [HEC258] MPG.PuRE
1Dasmahapatra, K. K., Walters, J. R., Briscoe, A. D., Davey, J. W., Whibley, A., Nadeau, N. J., Zimin, A. V., Hughes, D. S. T., Ferguson, L. C., Martin, S. H., Salazar, C., Lewis, J. J., Adler, S., Ahn, S.-J., Baker, D. A., Baxter, S. W., Chamberlain, N. L., Chauhan, R., Counterman, B. A., Dalmay, T., Gilbert, L. E., Gordon, K., Heckel, D. G., Hines, H. M., Hoff, K. J., Holland, P. W. H., Jacquin-Joly, E., Jiggins, F. M., Jones, R. T., Kapan, D. D., Kersey, P., Lamas, G., Lawson, D., Mapleson, D., Maroja, L. S., Martin, A., Moxon, S., Palmer, W. J., Papa, R., Papanicolaou, A., Pauchet, Y., Ray, D. A., Rosser, N., Salzberg, S. L., Supple, M. A., Surridge, A., Tenger-Trolander, A., Vogel, H., Wilkinson, P. A., Wilson, D., Yorke, J. A., Yuan, F., Balmuth, A. L., Eland, C., Gharbi, K., Thomson, M., Gibbs, R. A., Han, Y., C.Jayaseelan, J., Kovar, C., Mathew, T., Muzny, D. M., Ongeri, F., Pu, L.-L., Qu, J., Thornton, R. L., Worley, K. C., Wu, Y.-Q., Linares, M., Blaxter, M. L., ffrench-Constant, R. H., Joron, M., Kronforst, M. R., Mullen, S. P., Reed, R. D., Scherer, S. E., Richards, S., Mallet, J., McMillan, W. O., Jiggins, C. D., The Heliconius Genome Consortium (2012). Butterfly genome reveals promiscuous exchange of mimicry adaptations among species. Nature, 487, 94-98. doi:10.1038/nature11041. [HEC220] MPG.PuRE
2Kirsch, R., Wielsch, N., Vogel, H., Svatos, A., Heckel, D. G., Pauchet, Y. (2012). Combining proteomics and transcriptome sequencing to identify active plant-cell-wall-degrading enzymes in a leaf beetle. BMC Genomics, 13: 587. doi:10.1186/1471-2164-13-587. [HEC236] OPEN ACCESS gold MPG.PuRE
1Courtiade, J., Muck, A., Svatoš, A., Heckel, D. G., Pauchet, Y. (2011). Comparative proteomic analysis of Helicoverpa armigera cells undergoing apoptosis. Journal of Proteome Research, 10, 2633-2642. doi:10.1021/pr2001868. [HEC185] MPG.PuRE
2Courtiade, J., Pauchet, Y., Vogel, H., Heckel, D. G. (2011). A comprehensive characterization of the caspase gene family in insects from the order Lepidoptera. BMC Genomics, 12, 357. doi:10.1186/1471-2164-12-357. [HEC194] OPEN ACCESS gold MPG.PuRE
3Karatolos, N., Pauchet, Y., Wilkinson, P., Chauhan, R., Denholm, I., Gorman, K., Nelson, D. R., Bass, C., ffrench-Constant, R. H., Williamson, M. S. (2011). Pyrosequencing the transcriptome of the greenhouse whitefly, Trialeurodes vaporariorum, reveals multiple transcripts encoding insecticide targets and detoxifying enzymes. BMC Genomics, 12, 56. doi:10.1186/1471-2164-12-56. [HEC180] OPEN ACCESS gold MPG.PuRE
1Gahan, L., Pauchet, Y., Vogel, H., Heckel, D. G. (2010). An ABC transporter mutation is correlated with insect resistance to Bacillus thuringiensis Cry1Ac toxin. PLoS Genetics, 6: e1001248. doi:10.1371/journal.pgen.1001248. [HEC178] OPEN ACCESS gold MPG.PuRE
2Pauchet, Y., Wilkinson, P., Chauhan, R., ffrench-Constant, R. H. (2010). Diversity of beetle genes encoding novel plant cell wall degrading enzymes. PloS ONE, 5(12): e15635. doi:10.1371/journal.pone.0015635. [HEC176] OPEN ACCESS gold MPG.PuRE
3Pauchet, Y., Wilkinson, P., Vogel, H., Nelson, D., Reynolds, S., Heckel, D. G., ffrench-Constant, R. (2010). Pyrosequencing the Manduca sexta larval midgut transcriptome: messages for digestion, detoxification and defence. Insect Molecular Biology, 19(1), 61-75. doi:10.1111/j.1365-2583.2009.00936.x. [HEC137] MPG.PuRE
1Pauchet, Y., Freitak, D., Heidel-Fischer, H. M., Heckel, D. G., Vogel, H. (2009). Immunity or digestion: glucanase activity in a glucan-binding protein family from lepidoptera. Journal of Biological Chemistry, 284(4), 2214-2224. doi:10.1074/jbc.M806204200. [HEC105] OPEN ACCESS gold MPG.PuRE
2Pauchet, Y., Muck, A., Svatos, A., Heckel, D. G. (2009). Chromatographic and electrophoretic resolution of proteins and protein complexes from the larval midgut microvilli of Manduca sexta. Insect Biochemistry and Molecular Biology, 39(7), 467-474. doi:10.1016/j.ibmb.2009.05.001. [HEC117] MPG.PuRE
1Pauchet, Y., Muck, A., Svatos, A., Heckel, D. G., Preiss, S. (2008). Mapping the larval midgut lumen proteome of Helicoverpa armigera, a generalist herbivorous insect. Journal of Proteome Research, 7(4), 1629-1639. [HEC113] MPG.PuRE