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Research topic:

The cabbage stem flea beetle Psylliodes chrysocephala is a serious pest of oilseed rape and other crucifer crops. These plants are chemically defended by glucosinolates, which are converted to toxic isothiocyanates upon tissue damage. We previously observed that P. chrysocephala metabolizes isothiocyanates via the conserved mercapturic acid pathway. Because the first step of this metabolic detoxification pathway is usually catalyzed by glutathione S-transferases (GSTs), we hypothesize that GSTs play an important role in the detoxification of isothiocyanates in P. chrysocephala. The goal of my project is to characterize the function and evolution of glutathione S-transferases in this pest. This study will help to understand the molecular basis and importance of isothiocyanates detoxification in P. chrysochephala, and might reveal suitable targets for efficient pest control.

last updated on 2018-09-12