diwi3455

 PD Dr. Dieter Wicher

   Department of Evolutionary Neuroethology
   Reception & Transduction
 Phone:+49 (0)3641 57 1415Max Planck Institute for Chemical Ecology
 Fax:+49 (0)3641 57 1402Hans-Knöll-Straße 8
  emailD-07745 Jena

 Publications  Presentations  Teaching  help    to staff list 
2021
1Wicher, D., Miazzi, F. (2021). Insect odorant receptors: Function and regulation. In G. J. Blomquist, R. G. Vogt (Eds.), Insect Pheromone Biochemistry and Molecular Biology (Second Edition) (pp. 415-433). Amsterdam: Elsevier. doi:10.1016/B978-0-12-819628-1.00013-4. [HAN355] MPG.PuRE
2020
1Lucke, J., Kaltofen, S., Hansson, B. S., Wicher, D. (2020). The role of mitochondria in shaping odor responses in Drosophila melanogaster olfactory sensory neurons. Cell Calcium, 87: 102179. doi:10.1016/j.ceca.2020.102179. [HAN343] MPG.PuRE
2019
1Miazzi, F., Hoyer, C., Sachse, S., Knaden, M., Wicher, D., Hansson, B. S., Lavista Llanos, S. (2019). Optimization of insect odorant receptor trafficking and functional expression via transient transfection in HEK293 cells. Chemical Senses, 44(9), 673-682. doi:10.1093/chemse/bjz062. [HAN335] OPEN ACCESS gelb MPG.PuRE
2Wicher, D., Marion-Poll, F. (Eds.). (2019). Function and regulation of chemoreceptors. Lausanne: Frontiers Media. doi:10.3389/fncel.2018.00496. [HAN317] OPEN ACCESS gold MPG.PuRE
2018
1Halty, L., Hansson, B. S., Wicher, D. (2018). The Drosophila melanogaster Na+ /Ca2+ exchanger CALX controls the Ca2+ level in olfactory sensory neurons at rest and after odorant receptor activation. Frontiers in Cellular Neuroscience, 12: 186. doi:10.3389/fncel.2018.00186. [HAN313] OPEN ACCESS gold MPG.PuRE
2Miazzi, F., Kaltofen, S., Bello, J., Hansson, B. S., Wicher, D. (2018). Tissue embedding in a silica hydrogel for functional investigations. bioRxiv. doi:10.1101/357962. [HAN311] OPEN ACCESS gold MPG.PuRE
3Miazzi, F., Schulze, H.-C., Zhang, L., Kaltofen, S., Hansson, B. S., Wicher, D. (2018). Low Ca2+ levels in the culture media support the heterologous expression of insect odorant receptor proteins in HEK cells. Journal of Neuroscience Methods, 312, 122-125. doi:10.1016/j.jneumeth.2018.11.021. [HAN318] MPG.PuRE
4Wicher, D. (2018). Tuning insect odorant receptors. Frontiers in Cellular Neuroscience, 12: 94. doi:10.3389/fncel.2018.00094. [HAN306] OPEN ACCESS gold MPG.PuRE
5Wicher, D., Hansson, B. S. (2018). The Drosophila carbon dioxide receptor as key regulator of odor valence. Neuron, 97(5), 996-997. doi:10.1016/j.neuron.2018.02.014. [HAN300] OPEN ACCESS gold MPG.PuRE
2017
1Halty-deLeon, L., Wicher, D. (2017). Accessory proteins RTP1S and SNMP1 support the expression of the insect co-receptor Orco in mammalian culture cells (invited article summary about: Halty-deLeon L, Miazzi F, Kaltofen S, Hansson BS, Wicher D. (2016)) The mouse receptor transporting protein RTP1S and the fly SNMP1 support the functional expression of the Drosophila odorant coreceptor Orco in mammalian culture cells. J Neurosci Methods, 271, 149-53). Atlas of Science, 1-3. [HAN288] OPEN ACCESS gold MPG.PuRE
2Seki, Y., Dweck, H., Rybak, J., Wicher, D., Sachse, S., Hansson, B. S. (2017). Olfactory coding from the periphery to higher brain centers in the Drosophila brain. BMC Biology, 15: 56. doi:10.1186/s12915-017-0389-z. [HAN291] OPEN ACCESS gold MPG.PuRE
3Wicher, D., Große-Wilde, E. (2017). Chemoreceptors in Evolution. In J. Kaas (Ed.), Evolution of Nervous Systems 2e. (pp. 245-255). Oxford: Elsevier. [HAN285] MPG.PuRE
4Wicher, D., Morinaga, S., Halty-deLeon, L., Funk, N., Hansson, B. S., Touhara, K., Stengl, M. (2017). Identification and characterization of the bombykal receptor in the hawkmoth Manduca sexta. The Journal of Experimental Biology, 220(10), 1781-1786. doi:10.1242/jeb.154260. [HAN287] OPEN ACCESS gold MPG.PuRE
2016
1Getahun, M. N., Thoma, M., Lavista Llanos, S., Keesey, I., Fandino, R. A., Knaden, M., Wicher, D., Olsson, S. B., Hansson, B. S. (2016). Intracellular regulation of the insect chemoreceptor complex impacts odour localization in flying insects. Journal of Experimental Biology, 219, 3428-3438. doi:10.1242/jeb.143396. [HAN277] OPEN ACCESS gold MPG.PuRE
2Halty-deLeon, L., Miazzi, F., Kaltofen, S., Hansson, B. S., Wicher, D. (2016). The mouse receptor transporting protein RTP1S and the fly SNMP1 support the functional expression of the Drosophila odorant coreceptor Orco in mammalian culture cells. Journal of Neuroscience Methods, 271, 149-153. doi:10.1016/j.jneumeth.2016.07.005. [HAN273] MPG.PuRE
3Hansson, B. S., Wicher, D. (2016). Chemical ecology in insects. In F. Zufall, S. Munger (Eds.), Chemosensory Transduction: The Detection of Odors, Tastes, and Other Chemostimuli (pp. 29-45). London: Academic press. [HAN262] MPG.PuRE
4Miazzi, F., Hansson, B. S., Wicher, D. (2016). Odor-induced cAMP production in Drosophila melanogaster olfactory sensory neurons. Journal of Experimental Biology, 219(12), 1798-1803. doi:10.1242/jeb.137901. [HAN272] OPEN ACCESS gold MPG.PuRE
5Mukunda, L., Miazzi, F., Sargsyan, V., Hansson, B. S., Wicher, D. (2016). Calmodulin affects sensitization of Drosophila melanogaster odorant receptors. Frontiers in Cellular Neuroscience, 10: 28. doi:10.3389/fncel.2016.00028. [HAN260] OPEN ACCESS gold MPG.PuRE
6Wicher, D., Miazzi, F. (2016). Big tasks for small flies: signaling cascades may help insects to detect faint odor traces (invited article summary about: Miazzi F, Hansson BS, Wicher D (2016) Odor-induced cAMP production in Drosophila melanogaster olfactory sensory neurons. Journal of Experimental Biology, 219(12), 1798-1803). In Atlas of Science. Retrieved from http://atlasofscience.org/big-tasks-for-small-flies-signaling-cascades-may-help-insects-to-detect-faint-odor-traces/. [HAN282] OPEN ACCESS gold MPG.PuRE
2015
1Wicher, D. (2015). Olfactory signaling in insects. In R. Glatz (Ed.), Progress in Molecular Biology and Translational Science, Molecular Basis of Olfaction (pp. 37-54). Burlington: Academic Press. [HAN238] MPG.PuRE
2014
1Mukunda, L., Lavista Llanos, S., Hansson, B. S., Wicher, D. (2014). Dimerisation of the Drosophila odorant co-receptor Orco. Frontiers in Cellular Neuroscience, 8: 261. doi:10.3389/fncel.2014.00261. [HAN226] OPEN ACCESS gold MPG.PuRE
2Mukunda, L., Miazzi, F., Kaltofen, S., Hansson, B. S., Wicher, D. (2014). Calmodulin modulates insect odorant receptor function. Cell Calcium, 55, 191-199. doi:10.1016/j.ceca.2014.02.013. [HAN220] MPG.PuRE
2013
1Getahun, M. N., Olsson, S., Lavista Llanos, S., Hansson, B. S., Wicher, D. (2013). Insect odorant response sensitivity is tuned by metabotropically autoregulated olfactory receptors. PLoS One, 8(3): e58889. doi:10.1371/journal.pone.0058889. [HAN180] OPEN ACCESS gold MPG.PuRE
2Nolte, A., Funk, N., Mukunda, L., Gawalek, P., Werckenthin, A., Gawalek, P., Hansson, B. S., Wicher, D., Stengl, M. (2013). In situ tip-recordings found no evidence for an Orco-based ionotropic mechanism of pheromone-transduction in Manduca sexta. PLoS One, 8(5): e62648. doi:10.1371/journal.pone.0062648. [HAN185] OPEN ACCESS gold MPG.PuRE
3Wicher, D. (2013). Sensory receptors—design principles revisited. Frontiers in Cellular Neuroscience, 7: 1. doi:10.3389/fncel.2013.00001. [HAN176] OPEN ACCESS gold MPG.PuRE
4Wicher, D. (Ed.). (2013). Design principles of sensory receptors. Lausanne: Frontiers Media SA. doi:10.3389/978-2-88919-113-0. [HAN219] MPG.PuRE
2012
1Getahun, M. N., Wicher, D., Hansson, B. S., Olsson, S. (2012). Temporal response dynamics of Drosophila olfactory sensory neurons depends on receptor type and response polarity. Frontiers in Cellular Neuroscience, 6: 54. doi:10.3389/fncel.2012.00054. [HAN167] OPEN ACCESS gold MPG.PuRE
2Stensmyr, M. C., Dweck, H., Farhan, A., Ibba, I., Strutz, A., Mukunda, L., Linz, J., Grabe, V., Steck, K., Lavista Llanos, S., Wicher, D., Sachse, S., Knaden, M., Becher, P. G., Seki, Y., Hansson, B. S. (2012). A conserved dedicated olfactory circuit for detecting harmful microbes in Drosophila. Cell, 151(6), 1345-1357. doi:10.1016/j.cell.2012.09.046. [HAN172] OPEN ACCESS gold MPG.PuRE
3Wicher, D. (2012). Functional and evolutionary aspects of chemoreceptors. Frontiers in Cellular Neuroscience, 6: 48. doi:10.3389/fncel.2012.00048. [HAN173] OPEN ACCESS gold MPG.PuRE
2011
1Grosse-Wilde, E., Kuebler, L., Bucks, S., Vogel, H., Wicher, D., Hansson, B. S. (2011). Antennal transcriptome of Manduca sexta. Proceedings of the National Academy of Sciences of the United States of America, 108(18), 7449-7454. doi:10.1073/pnas.1017963108. [HAN112] OPEN ACCESS gold MPG.PuRE
2Olsson, S., Getahun, M. N., Wicher, D., Hansson, B. S. (2011). Piezo controlled microinjection: An in vivo complement for in vitro sensory studies in insects. Journal of Neuroscience Methods, 201(2), 385-389. doi:10.1016/j.jneumeth.2011.08.015. [HAN124] MPG.PuRE
3Sargsyan, V., Getahun, M. N., Lavista Llanos, S., Olsson, S., Hansson, B. S., Wicher, D. (2011). Phosphorylation via PKC regulates the function of the Drosophila odorant coreceptor. Frontiers in Cellular Neuroscience, 5: 5. doi:10.3389/fncel.2011.00005. [HAN122] OPEN ACCESS gold MPG.PuRE
2010
1Grosse-Wilde, E., Stieber, R., Forstner, M., Krieger, J., Wicher, D., Hansson, B. S. (2010). Sex-specific odorant receptors of the tobacco hornworm Manduca sexta. Frontiers in Cellular Neuroscience, 4: 22. doi:10.3389/fncel.2010.00022. [HAN080] OPEN ACCESS gold MPG.PuRE
2Hansson, B. S., Knaden, M., Sachse, S., Stensmyr, M., Wicher, D. (2010). Towards plant-odor-related olfactory neuroethology in Drosophila. Chemoecology, 20(2), 51-61. doi:10.1007/s00049-009-0033-7. [HAN065] MPG.PuRE
3Seki, Y., Rybak, J., Wicher, D., Sachse, S., Hansson, B. S. (2010). Physiological and morphological characterization of local interneurons in the Drosophila antennal lobe. Journal of Neurophysiology, 104(2), 1007-1019. doi:10.1152/jn.00249.2010. [HAN078] OPEN ACCESS gold MPG.PuRE
4Wicher, D. (2010). Design principles of sensory receptors. Frontiers in Cellular Neuroscience, 4: 25. doi:10.3389/fncel.2010.00025. [HAN083] OPEN ACCESS gold MPG.PuRE
2009
1Wicher, D., Schäfer, R., Bauernfeind, R., Stensmyr, M. C., Heller, R., Heinemann, S. H., Hansson, B. S. (2009). dOr83b - receptor or ion channel? Annals of the New York Academy of Sciences, 1170(1), 164-167. doi:10.1111/j.1749-6632.2009.04101.x. [HAN084] MPG.PuRE
2008
1Wang, S., Huang, L., Wicher, D., Chi, C., Xu, C. (2008). Structure-function relationship of bifunctional scorpion toxin BmBKTx1. Acta biochimica et biophysica Sinica, 40(11), 955-963. doi:10.1111/j.1745-7270.2008.00479.x. [HAN056] OPEN ACCESS gold MPG.PuRE
2Wicher, D., Schäfer, R., Bauernfeind, R., Stensmyr, M. C., Heller, R., Heinemann, S. H., Hansson, B. S. (2008). Drosophila odorant receptors are both ligand-gated and cyclic-nucleotide-activated cation channels. Nature, 452(7190), 1007-1011. doi:10.1038/nature06861. [HAN040] MPG.PuRE
2007
1Dedos, S. G., Wicher, D., Kaltofen, S., Birkenbeil, H. (2007). Different Ca2+ signalling cascades manifested by Mastoparan in the prothoracic glands of the tobacco hornworm, Manduca sexta, and the silkworm, Bombyx mori. Archives of Insect Biochemistry and Physiology, 65 (2), 52-64. doi:10.1002/arch.20180. [HAN034] MPG.PuRE
2Wicher, D. (2007). Metabolic regulation and behavior: how hunger produces arousal – an insect study. Endocrine, Metabolic & Immune Disorders - Drug Targets, 7(4), 304-310. doi:10.2174/187153007782794290. [HAN035] MPG.PuRE
3Wicher, D., Derst, C., Gautier, H., Lapied, B., Heinemann, S., Agricola, H.-J. (2007). The satiety signaling neuropeptide perisulfakinin inhibits the activity of central neurons promoting general activity. Frontiers in Cellular Neuroscience, 1: 3. doi:10.3389/neuro.03.003.2007. [HAN036] OPEN ACCESS gold MPG.PuRE
2006
1Wicher, D. (2006). Metabolische Regulation und neuronale Aktivität: Wie Hunger mobil macht. Neuroforum, 3 (06), 228-229. doi:10.1515/nf-2006-0304. [HAN009] MPG.PuRE
2Wicher, D., Agricola, H. J., Söhler, S., Gundel, M., Heinemann, S. H., Wollweber, L., Stengl, M., Derst, C. (2006). Differential receptor activation by cockroach adipokinetic hormones produces differential effects on ion currents, neuronal activity, and locomotion. Journal of Neurophysiology, 95(4), 2314-2325. doi:10.1152/jn.01007.2005. [HAN061] OPEN ACCESS gold MPG.PuRE